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Therefore, monitored clinical trials should be performed to examine whether adding antioxidative agents to standard treatment is safe and if doing so may improve the prognosis or reduce hospitalization in COVID-19 patients

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The protein concentration was quantified using a BCA kit, and then SDS-PAGE buffer was added

Importantly, metabolomic data revealed concurrent reductions in collagen biosynthesis intermediates (trans-3-hydroxy-L-proline, glycine, L-proline) and fibroblast-activating lysophospholipids, supporting that Retatrutide induces coordinated suppression of pro-fibrotic programs at both transcriptional and metabolic levels