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Never shake or vortex the vial , the mechanical stress from shaking can break the peptide structure and promote aggregation

PloS One 9 (9):e106538 Xie Q, Liao Q, Wang L, Zhang Y, Chen J, Bai H, Li K, Ai J (2024) The dominant mechanism of cyclophosphamide-induced damage to ovarian reserve: premature activation or apoptosis of primordial follicles