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Description

We also generated hybrid organoids mixing mutated and control progenitors to assess the role of each cell type in determining the disease phenotype

Since in some cases gshA and gshB fuse to form a single gene gshF and sequence divergence is very high for both GshA and GshB [3], the results of GshA, GshB and GshF were manually checked for the position of alignment in the gene and length of the hit