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For the cyst and reniform nematodes this takes the form of a large syncytium that arises through local cell wall dissolution and fusion of neighbouring protoplasts

In this regard, Fmoc SPPS is at the forefront in the design of therapeutic peptides since it permits the easy alteration of features such as hydrophobicity, polarity, charge, structure, and it may also enhance activity and overcome the limitations of natural peptides (Freitas and Franco, De novo peptide design may help reducing production costs, potential toxicity and lability, as well as increasing the in vivo activity (Steckbeck et al., 2014)