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Under normal physiological conditions, the microglia remain quiescent

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Increase cortisol level has been linked with anxiety like behavior [9]

Inherited Disorders of Folate Transport and Metabolism Several inherited disorders of folate metabolism and transport have been described [4] (see Table 2 ), for example: MTHFR deficiency, MTR deficiency (either caused by mutations in MTR gene or MTRR gene), ecerebral folate deficiency ( CFD ) (caused by FOLR1 mutation), hereditary folate malabsorption, and glutamate formiminotransferase ( FTCD ) deficiency