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AIFA in Italy and other regulatory authorities where marketed)

Dietary and lifestyle factors along with state-of-the-art natural compounds targeting both the skin manifestations and systemic inflammation of psoriasis will be discussed as well

These targets likely contribute to the ATF4-dependent inhibition of mTORC1 signaling (S6K1 phosphorylation) observed upon tunicamycin treatment (Figure 1B), while in the context of mTORC1 signaling, these ATF4 targets might play a role in negative feedback regulation of mTORC1