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Establishing a diagnosis of PHG disease caused by HSV-1 infection actually could be seen from the patients anamnesis and clinical examination, such as in the study by Turton et al which stated that the characteristics of perioral vesicles, ulcers in the oral cavity including the gingiva, inflammation of the gingival margin area and starting with prodromal symptoms are very common symptoms in PHG without conducting supporting examinations

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Medicine, Angioplasty, or Surgery Study (MASS-II) showed no difference in cardiac death or acute MI among patients in CABG, PCTA, or medical treatment groups

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