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For each titration, the average value from a one-minute interval at stable OCR was used for data analysis

These acylcarnitines can be exported from the mitochondria and cell, preventing the toxic accumulation of acyl-CoA intermediates that inhibit key metabolic enzymes

The absolute bioavailability of levocarnitine from the two oral formulations of CARNITOR , calculated after correction for circulating endogenous plasma concentrations of levocarnitine, was 15.1 5.3% for CARNITOR Tablets and 15.9 4.9% for CARNITOR Oral Solution

Furthermore, imatinib that is the first-line treatment of patients with chronic myeloid leukemia seems to be transported in cells by OCTN2 and OCTN1 (Hu et al., 2008 and Table 1)