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Community sources commonly describe cycles of 4-8 weeks on, 2-4 weeks off, citing the desire to assess off-cycle effects and the absence of long-term safety data as the rationale

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It is a peptidomimetic (a small protein-like chain designed to mimic a peptide) composed of two functional domains: a homing domain and a pro-apoptotic domain

Bottom line: the largest weight-loss signal of any obesity peptide so far about 24% mean loss at 48 weeks in a phase 2 trial but investigational only, now in phase 3 (the TRIUMPH program) and not approved by any regulator