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Physiol Rev 74:139162

These studies indicate that overproduction of glutathione drives the survival and growth of a small subset of lymphoid tumor cells in 3D gels and xenografts, likely TIC or TIC-like cells, and that glutathione is selectively required for tumor growth in females of a mouse model of lymphoma

Physiologically in the eye when you develop a cataract, researchers have found that the ascorbic acid and glutathione levels in the aqueous that surrounds the cataract become decreased