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Description

[DOI] [PMC free article] [PubMed] [Google Scholar] 47.Nijhof IS, et al

doi:10.1212/wnl.44.5.796 Barton JJ

Anti-inflammatory effects reduce swelling and pain, which supports functional recovery and movement restoration

Skin mast cells carry MRGPRX2, a receptor that fires on cationic, aromatic ("cationic amphiphilic") molecules and releases histamine redness, swelling, the classic wheal. It is confirmed for SS-31, which activates the receptor well below its injection concentration