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The lack of glutathione may result in fatigue, frequent occurrence of cold, and anemia

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The GG genotype lowers homocysteine but raises risk for: Systemic lupus erythematosus Bipolar disorder Schizophrenia Congenital facial and spinal malformations Down syndrome Methionine Synthase Reductase: An AG substitution at base pair 66 affects ~ 30% of individuals

Glucose, insulin, homeostatic model assessment for insulin resistance, glutathione peroxidase, superoxide dismutase, oxidized LDL, and malondialdehyde did not significantly change after 4 weeks in any group