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The observed decrease in MCP-1 staining intensity suggests that intranasal administration of GHK-Cu in transgenic 5xFAD mice had a reducing effect on the AD-induced inflammatory phenotype and could serve as a reliable prototype to study drugs that slow or stop progression of AD [40]

In a t-BHP-induced hepatotoxicity model study, fermented rooibos consumption by rats reversed the elevation in serum aminotransferases and lactate dehydrogenase induced by t-BHP [211]

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Thyroid hormone receptor (THR) agonists, and ACC inhibitors are used to reduce hepatic fat synthesis and promote fatty acid oxidation, thereby reducing hepatic fat content