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Meanwhile, DDM has low immunogenicity and does not cause severe inflammatory reactions in the host [17], making it an ideal choice for bone graft substitute

Further, decrease in levels of B 12 demonstrated in patient with multiple sclerosis (Miller et al., 2005)

The search included articles published between 2010 and 2025, using keywords: Parkinsons disease, -synuclein, dopaminergic degeneration, ferroptosis, deep brain stimulation, stem cell therapy, and AI in PD diagnosis. Results: The review highlights a multifactorial etiology involving -synuclein pathology, oxidative stress, mitochondrial dysfunction, genetic mutations (SNCA, LRRK2, VPS35), environmental toxins, and gut dysbiosis

The mice were housed in ventilated cages in a humidity- and temperature-controlled room (temperature, 22 2 C