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For example, PLP is required for the synthesis of neurotransmitters such as GABA and serotonin, for heme biosynthesis (through -amino levulinate synthase in red blood cell production), and for amino acid transformations

The 19 identified GLP-1 RA-related NAEs are not documented in approved labeling, expanding on prior evidence

Ideal for accurate measurement and compound reconstitution

Whether those studies establish a sufficient benefit-risk profile for human use through compounding pharmacies was the core scientific question, and the committee's majority answered yes over the objections of FDA scientists who answered no