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In: Parnham MJ, Bruinvels J (eds) Discoveries in pharmacology, volume I: psycho- and neuro-pharmacology

Peptide origin / Partial sequence of human gastric protein BPC, isolated from gastric juice Molecular weight / Approximately 1,419 Da (15 amino acids) Common off-label oral dose / 250 to 500 mcg twice daily, taken on an empty stomach Common off-label subcutaneous dose / 200 to 300 mcg once or twice daily near the affected area or abdominally Evidence level / Preclinical only (GRADE: very low certainty for human GI healing) Key preclinical finding / Accelerated gastric ulcer healing in rats within 24 to 72 hours across multiple models Route preference for GI targets / Oral administration, based on topical mucosal contact rationale Safety profile in humans / Largely unknown

E08 Diabetes Mellitus Due to Underlying Condition E09 Drug or Chemical Induced Diabetes Mellitus E10 Type 1 Diabetes Mellitus E11 Type 2 Diabetes Mellitus (Most Commonly Used) E13 Other Specified Diabetes Mellitus E13 applies to post-pancreatectomy diabetes, MODY, neonatal diabetes, and other forms not captured by E08 to E11

View Study Dou Y, Lee A, Zhu L, Morton J, Ladiges W The potential of GHK as an anti-aging peptide