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The occurrence of ferroptosis is often accompanied by the dysregulation of the intracellular antioxidant system, particularly the loss of function of GPX4, which significantly reduces the cells ability to defend against lipid peroxidation ( Figure 1 )

FIGURE 3 GO and KEGG analyses of the 59 aforementioned candidate targets indicated that the biological process (BP) terms of the target genes were mainly involved in the positive regulation of cell proliferation (GO:0008284), protein phosphorylation (GO:0006468), positive regulation of cell migration (GO:0030335), and negative regulation of apoptosis (GO:0043066)

Largely through the work of Dr

Glutamine is the most abundant amino acid found in the human body