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J Pathol 190:489-494 LP James, Capparelli EV, Hinson JA, Dalvern TJ, Lee WM (2007) Pharmacokinetic analysis of acetaminophen protein adducts in adults with acute liver failure

Acta Neuropathologica 128 (2): 247266

One such pathway is the metabolic shift from tryptophan (TRP) to kynurenine (KYN), which has been strongly associated with depression development (91, 92)