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Numbness, tingling in hands, legs and feet (as a result of nerve damage which is triggered by low oxygen levels in cells) Muscle weakness and coordination problems Mental problems such as depression, anxiety, memory loss, changes in behaviour Fertility issues and recurring early miscarriage So if you have any of the above symptoms it would be worth getting your B12 levels tested by your health practitioner as you may need supplementation or B12 injections for more severe cases

Yes, a small, temporary red mark or a slight bump (wheal) at the injection site is very common and usually not a cause for concern

doi: 10.1152/japplphysiol.01222.2011

Then methionine level increases and related methyl group donation is driven which successively exert potential mechanism on psychiatric diseases, as shown in Fig