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The MPTP has been suggested to consist of Bax, along with the protein Bak on the mitochondrial outer membrane69,70, with the c-subunit ring of the F 1 F O ATP synthase71 being one of the regulatory components within the inner membrane

However, the precise interaction between glial cells and neurons is controlled by various mechanisms that still require further investigation using advanced technologies like microfluidic systems, 3D cultures, and in vivo imaging