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However, the researchers concluded based on their review that a beneficial effect of a gluten free diet may be expected, since in general, in children as well as in adults, intestinal inflammation and the associated dysbiosis, with or without underlying celiac disease, are known to promote extra intestinal autoimmune diseases. Therefore, any measure, including a gluten-free diet, that would help to manage gut inflammation in celiac disease patients may positively impact the evolution and perhaps the manifestation of thyroid autoimmunity

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Female patients, smokers, gastric and mixed ulcer patients, patients with GERD or chronic diseases, subjects with chronic NSAIDs intake or regular intake of acid-inhibitory drugs, antibiotics or antioxidants in the preceding one month of the study