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[] However, the source of TNFSF14 in this study is unclear

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Under physiological conditions, Nrf2 binds to Keap1 located in the cytoplasm to form a dimer, but after oxidative stress occurs, Keap1 undergoes conformational changes due to electrophilic or oxidative signal modification, thereby releasing Nrf2 into the cell nucleus (Liu et al., 2022b)

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