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Recent bioinformatic analyses based on GEO datasets (GSE51588 and GSE55457) identified LPCAT3 as one of the ferroptosis-related differentially expressed genes significantly downregulated in OA tissues

Thus, iron overload and metabolism dysfunction was thought to play a pivotal role in mTBI pathophysiology

plasmid #136466, Watertown, MA, United States) plasmids were performed with the transfection reagent FuGENE HD (Promega, Ref: E2311, Promega GmbH, Walldorf, Germany) at a 2:1 FuGENE HD:DNA ratio according to the manufacturer protocol