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6.1 Future directions Although there is no strong evidence currently to corroborate melatonin as a powerful antioxidant and anti-inflammatory in the placenta during oxidative stress, inflammation, and viral infection, future work should address whether melatonins antioxidant properties in the placenta are due to direct scavenging of ROS (supraphysiological) or receptor-mediated (physiological)

Metformin is recommended as the first-line treatment for type 2 DM, as it can improve endothelial dysfunction by enhancing endothelium-dependent vasodilation and reducing sympathetic overactivity, ultimately restoring erectile responses in the CC of DM animal models through the NO/cGMP pathway [168]

The reduced molecular complexity of fragments also means they tend to have weaker potency and typically bind to targets with higher hit rates at millimolar to micromolar affinity

Made up of amino acids, Glutathione is a powerful antioxidant and detoxifier