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A-to-G mutation at nuclcotide position 3243 was originally identified in MEI.AS syndrome (mitochondrial myopathy, encephalopathy, lactic acidosis and stroke-like episodes) and accounted for about 80% of the MELAS cases, Recently, this mutation was reported in maternally inherited NIDDM patients

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Physiol Res 73(4):621631 Dumitrescu L, Marta D, Dnu A, Lefter A, Tulb D, Cozma L, Manole E, Gherghiceanu M, Ceafalan LC, Popescu BO (2021) Serum and fecal markers of intestinal inflammation and intestinal barrier permeability are elevated in Parkinsons disease