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Yim MB, Kang JH, Yim HS, Kwak HS, Chock PB, et al

When folate supply to the rapidly dividing cells of the bone marrow is inadequate, blood cell division is reduced, resulting in fewer but larger red blood cells

This pathway is slow in the cytosol but might be efficient in membrane-rich cellular compartments such as chloroplasts and mitochondria owing to the lipophilic nature of NO and O 2 (Liu et al., 1998