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This innovation is not just about increasing the concentration of hyaluronic acid but also about enhancing its delivery mechanism to achieve superior skin hydration

Although the maximum plasma concentration is lower when compound 2 is administered PO (0.77 M) instead of IP (4.8 M), it is still 4.3-fold higher than LD 50 for ex vivo NTS determined in the commonly used 72 h assay, also indicating that TGR inhibitor 2 is orally bioavailable and the initial prediction of oral bioavailability based on the Lipinski et al

(2024) 84(6_Supplement):1500

Unlike traditional options such as minoxidil and finasteride, GHK-Cu is non-hormonal, well tolerated, and provides added benefits for skin and tissue repair