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B12 supplementation is appropriate for individuals with confirmed deficiency, vegans, older adults, those with malabsorption disorders, people who have had bariatric surgery, and those on long-term medications such as metformin or proton pump inhibitors

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Many people live with low-grade chronic inflammation for years without realizing its the root cause of their ongoing physical challenges

C.ComeroS.LocoroG.TavazziS.et al (2013)