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Patients with MCAS may experience: Flushing Urticaria (hives) and itching Gastrointestinal distress Brain fog Tachycardia Headaches Hypotension Respiratory symptoms Anaphylactoid reactions Because mast cells reside throughout connective tissues, symptoms are often multisystem, variable, and unpredictable

J., Shaw P

Postuma RB, Espay AJ, Zadikoff C, et al

Data on study type (e.g., randomized controlled trial (RCT), randomized crossover trial, observational study), treatment parameters (e.g., dose, administration protocols, follow-up durations), patient characteristics (i.e., age, gender, symptom duration), AEs, and primary outcomes (as defined by study authors) were extracted