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Diagnoses of psychiatric or aective disorders were determined by asking the following questions: Do you have a psychiatric or aective diagnosis? Have you taken a pharmacological treatment or received psychological therapy? Additionally, some medical conditions exceed the normal range of hematological parameter counts and antioxidant levels

R., Burd, P

Prospective clinical pharmacokinetic studies should therefore directly quantify dobutamine concentrations during hemoadsorption and determine whether the observed sorbent interaction translates into a clinically meaningful increase in total clearance that would justify dose adaptation

10.1038/s41586-019-1705-2 Nature 13 BorgesK.GearingM.McDermottD