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Folate-sodium alginate-cholesterol nanoparticles delivering doxorubicin and metformin achieved targeted accumulation and induced various forms of programmed cell death, including necroptosis, apoptosis, and pyroptosis in xenograft melanoma tumors (Song et al., 2021)

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Previous studies have emphasized the importance of epigenetic changes, such as DNA methylation, histone modifications and chromatin remodeling, in the development of endometriosis (107109)