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Davis et al., 2023) casecontrol studies may have been subject to selection bias because of low participation rates, if those who chose to participate varied from the source population in terms of sweetener use

ROS can influence DNA methylation levels by the oxidation of guanosine to 8-oxo-2-deoxyguanosine (8-oxo-dG) or by hydroxyl radicals that via abstraction of a hydrogen from the methyl group of mC leads to the formation of 5hmC (Madugundu et al., 2014)

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