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Examples include putting into the needles magnesium nanoparticles that will react explosively with interstitial fluid 29 , creating of the DMNs with fast dissolving drug-loaded needle tips 30 , fabricating of needles that can swell/dissolve upon the application of electricity 31 , making needles to be heat responsive 32 , and using acidbase reaction that can generate gas at the junction between needles and the base 33

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Like, influenza, as we know, every year we go through a process of selecting what strains should be in the annual influenza vaccination, and that's been going on forever, and I have a feeling that that's going to be the same scenario for SaRS-CoV-2, at least for the near future, but probably the distant future as well