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Improved mental health also plays a major role here

10.1016/S0140-6736(98)07546-1

At the immunological level, a central role has been established for the imbalance between T helper 1 cell (Th1)/T helper 17 cell (Th17) and Regulatory T cell(Treg cell) subsets [7] and for excessive activation of innate immune receptors [8]