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In addition, we found that autophagy is activated in the process of ferroptosis and reduces SIPS, suggesting an essential role of autophagy in ferroptosis and SIPS

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Both fermented and unfermented rooibos extracts (5% and 10%, w/v) were significantly effective against 2-acetylaminofluorene (2-AAF) and aflatoxin B 1 (AFB 1 )-induced mutagenesis in the mutagenicity assay (tester strain TA98 and TA100) in the presence of metabolic activation with S9

Innovative drug delivery systems are being developed to improve the bioavailability and tumor targeting of GPX4 inhibitors like RSL3 and FIN56, while minimizing off-target effects on normal tissues