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At the cellular level, elevated Hcy disrupts the retinal blood barrier and increases pigment epithelial cell inflammatory cytokines, which cause retinal apoptosis [101]

Goronzy, S.J

Ginkgo biloba leaf extract attenuates atherosclerosis in streptozotocin-induced diabetic ApoE-/- mice by inhibiting endoplasmic reticulum stress via restoration of autophagy through the mTOR signaling pathway

It has even been proposed that NNMT be considered as a novel and sensitive serum biomarker for detecting colorectal cancer, outperforming the clinical significance of carcinoembryonic antigen (CEA) (42)