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Rubicon inhibits autophagy and accelerates hepatocyte apoptosis and lipid accumulation in nonalcoholic fatty liver disease in mice

doi: 10.1016/j.cmet.2020.10.011 55 CiminiEPiacentiniPSacchiAGioiaCLeoneSLauroGMet al

Recent studies have provided evidence for the existence of at least two classes of plasma membrane GSH exporters (Ballatori et al., 2005, 2008)

While this cytokine storm is biologically necessary for acute survival, it generates an astronomical amount of reactive oxygen species (ROS) as a byproduct of immune cell activation