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After multiple doses, mean IGF-I remained above baseline for up to 28 days , with evidence of a cumulative effect

[312] Consumption of coffee and tea, particularly 2-3 cups of coffee and more than 4 cups of tea per day, is associated with increased macular retinal nerve fiber layer (mRNFL) thickness, suggesting potential neuroprotective effects that warrant further investigation into causal links and mechanisms

Such models are useful in studying metabolic and developmental consequences of thyroid hormone deficiencies, giving insight into how thyroid hormone insufficiency impacts growth and neurological function

Barnham KJ, Masters CL, Bush AI