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The Role of Leptin and Adiponectin in Obesity-Associated Cognitive Decline and Alzheimers Disease

There is no tolerable upper intake level (UL) set for vitamin B12, so you technically cant take too much

PMID 11210144

In our review, some ( Patients with vitamin B12 deficiency who are symptomatic have severe neurological deficits or have critically low blood levels of vitamin B12 should be treated with IM administration