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[PubMed] [Google Scholar] 31.Wall BT, Stephens FB, Constantin-Teodosiu D, Marimuthu K, Macdonald IA, Greenhaff PL

It acts as an effective antioxidant, supporting many metabolic functions of sperm, such as maturation and energy metabolism

15,16 One setting in which metformin is sometimes considered first-line treatment is in adolescents with PCOS, although oral contraceptives are important as well