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Conversely, selective activation of oxysterol-responsive receptors such as LXRs and Gpr183 can promote oligodendrocyte differentiation and remyelination, underscoring the context-dependent duality of oxysterol signaling in neurodegeneration

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However, its function in vivo remains poorly understood

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Front Neurol 12:650752 Kim J, Hemachandran S, Cheng AG, Ricci AJ (2022) Identifying targets to prevent aminoglycoside ototoxicity

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