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The observed increase in mitochondrial malate and cytosolic 2-oxoglutarate through elevated SLC25A11 expression aligns with the systemic energetic dysregulation and oxidative stress reported in plasma metabolomic studies in ME/CFS patients

This powerful effect was particularly important during the peak outbreak of COVID-19 where it was suggested as a possible supplement to help suppress the widespread inflammation often leading to organ failure

Moreover, blending the extracts with the known anticancer drug 5-fluoruoracil boosted cell cytotoxicity

Selank is primarily associated with anxiety reduction, while Semax is often used for cognitive support