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PMID: 27531233

When SNC-80 and ARM-390 are chronically administrated, tolerance to analgesia develops and is dependent on endocytosis with SNC80 but not for ARM-390

I., Almurayshid A., Jung J

In aged kidneys, the presence of invasive macrophages and lymphocytes results in a decrease in renal mass primarily through mechanisms of tubular fibrosis and atrophy (Mei and Zheng, 2009)