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Probiotics, such as Lactobacillus and Bifidobacterium, can regulate the cytokine profile, promoting the production of anti-inflammatory cytokines and inhibiting the expression of pro-inflammatory cytokines [66, 104,105,106,107]

These interventions effectively suppress the efficient synthesis of immunosuppressive proteins such as programmed death-ligand 1 (PD-L1) in tumor cells