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These cytokines promote osteoclastogenesis and precipitate bone loss (179)

JR has received consultation fees from Merck Serono

However, targeting of IFN / IFNGR1 can directly have pleotropic effects 29 , as indicated by our finding that IFNGR1 knockout tumors were significantly larger than IFNGR1 wild-type tumors in mice treated with IgG control

4 Discussion The rise of multidrug-resistant bacteria represents a significant threat to public health, and this threat is primarily driven by the overuse of clinical antibiotics