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Dehnes et al., 2008)

The mirror is nicer to you

Discontinue use if irritation, prolonged redness, or allergic reaction occurs

Given the limitations on measuring drug concentrations at time zero and using the aforementioned formula, the measured concentration of highly lipid-soluble drugs can be low enough to result in a value of Vd c that is greater than 1 L/kg, so it is often referred to as an apparent volume of distribution