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Transdermal patches are being tested and developed for different medical applications, making way for FDA-approved GLP-1 transdermal patches in the future

Treatment of Mecp2 mutant mice with IGF1 significantly increases spine density (with no mention of improvements in dendritic arbor

We also discuss how these developments are providing important lessons for the emerging second generation of combinatorial ('SMN-plus') therapies that are likely to be required to generate robust treatments that are effective across a patient's lifespan

Astrocytes are key in maintaining the BBB, blood flow, and neuronal metabolism [82, 83]