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In patients receiving daratumumab as first subsequent therapy, median PFS was lower in the isatuximab-Pd treated patients (2.2 months [95% CI 0.037.62], n = 9) than the Pd-treated patients (5.1 months [95% CI 3.7510.51], n = 46) [79]

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While cyanocobalamin has proved effective in preventing vitamin B12 deficiency, there is increasing evidence that the coenzyme B12 forms have a distinct advantage and better spectrum of action in many specialised applications

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