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Activated microglia disrupt the blood-brain barrier and induce chemokines and cytokines in a rat in vitro model

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GHK-Cu (glycine-L-histidine-lysine) is a small copper-binding peptide, which has a remarkable and well-documented ability to improve wound healing and tissue regeneration, regulate remodeling of connective tissue and synthesis of collagen, elastin and glycosaminoglycans, reduce inflammation and scarring, increase antioxidant-enzymes and protect cells from toxic by-products of lipid peroxidation