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concentration of this substrate in the initial, uninoculated, culture medium is typically greater than about 2% w/v, more typically between about 2% and 10% w/v, more typically between about 3% and 8% w/v

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Sulforaphane (246), resveratrol (247), coenzyme Q10 (248), NAC (249), omega-3 fatty acids (250), arachidonic acid, and DHA (251) are some of the antioxidant supplements used in these studies to treat ASD

However, pharmacological targeting of glutamate metabolism is therapeutically challenging, due to the pronounced side effects of the anti-glutamatergic drugs [124] and the complex glioma microenvironment [125]